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NAT Ketones Reviews
Updated on February 27, 2023
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NAT Ketones Reviews

If you have any interest in fitness, diet, or nutrition, you’ve probably come across the ketogenic diet. The ketogenic diet, or keto diet for short, is a very low-carbohydrate, high-fat diet that causes the body to burn fat for fuel instead of glucose. The keto diet has been shown to improve blood sugar levels, improve cognitive function, and help with weight loss.1,2 

However, the keto diet can be hard to stick to because it’s very restrictive. A person who normally eats 2,000 calories a day has to limit their carbohydrates to less than 50 g/day.1 This means you have to cut out bread, pasta, potatoes, and most fruits. Not many people have the willpower to do this long term.    

For those who want to get the benefits of a keto diet without following a strict diet, there are ketone supplements like Keto OS NAT by Prüvit. Ketone supplements supply your body with the same ketones your body makes naturally. 

But do they actually work, are they safe, and do you get the same benefits as you would eating a keto diet? I tried Keto OS NAT for a month to help answer these questions for you.  

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Will Hunter / KnowYourDNA

Quick Facts on Prüvit’s NAT Ketones Drink

  • Contains a patented blend of ketones, vitamins, and minerals designed to support energy, focus, immune function, and athletic performance
  • Supplies your body with the same ketones it makes naturally 
  • Quickly raises ketone levels and puts you into ketosis within 60 minutes

What is Keto OS NAT?

Ketone Operating System Nutritionally Advanced Technology, or Keto OS NAT for short, is a comprehensive ketone supplement powder. It’s available in bulk powder individual packets. 

Ketones are compounds made naturally by the liver that serve as an alternative energy source when your body isn’t able to use glucose. When your body is running off of ketones, it’s in a state of ketosis. 

There are two categories of ketones:

  • Endogenous ketones. These are the ketones your body makes naturally when it’s in ketosis.
  • Exogenous ketones. These are the ketones that come from a supplement. These most often come in the form of ketone salts, which helps the body absorb them better.    

Your body enters ketosis when you’re eating a very low-carbohydrate diet or fasting. Uncontrolled diabetes can also cause a dangerous form of ketosis that can result in serious harm, coma, and even death if not treated. You can also enter a state of ketosis by taking ketone supplements.  

Keto OS NAT supplies the same ketones your body makes naturally during ketosis. This means you can experience many of the benefits of ketosis without having to follow a strict low-carb ketogenic diet. 

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Keto OS NAT Ingredients (What’s Inside?)

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Keto OS NAT contains a proprietary blend called N8 Max NAT that includes:

  • R-Beta-hydroxybutyrate, one of the three types of ketones made naturally in the body   
  • L-Taurine, an amino acid that supports heart health and brain health, energy production, and fluid balance   
  • L-Leucine, an amino acid that promotes muscle gain  
  • C-Med 100, a patented extract of the inner bark of Cat’s Claw plant that helps with inflammation and DNA repair3

Keto OS NAT also contains:

  • Vitamin B12
  • Vitamin B6
  • Calcium 
  • Magnesium
  • Sodium
  • Caffeine

Keto OS NAT is sweetened with erythritol and stevia extract.  

The B vitamins in Keto OS NAT provide extra energy. The amino acids and electrolytes support hydration, muscle function, and nervous system function.  

There are two versions of Keto OS NAT: one that contains caffeine called “Charged” and a caffeine-free version called “Uncharged.” 

How Much Does Keto OS NAT Cost?

Keto OS NAT costs $130 per box for a one-time purchase (20 servings). 

You can also sign up for a monthly subscription which lowers the cost to $101.40 per box.   

How Do Keto OS Supplements Work?

Keto OS NAT works by supplying your body with ketones so your body doesn’t have to make them. It contains beta-hydroxybutyrate, the ketone that has the most research behind it.

Taking ketone supplements boosts your blood ketone levels quickly which allows your whole body–including your brain and muscles–to use them as an energy source. 

Keto OS NAT is designed to put you into ketosis fast–within an hour. Contrast this to the time it takes you to reach ketosis by following a ketogenic diet: severals days to weeks.4 

Instead of fasting or needing to closely monitor your carbohydrate, protein, and fat intake, you can simply supplement with Keto OS NAT. Prüvit claims that their product can deliver the same benefits you would get following a ketogenic diet such as more energy, better focus and concentration, and enhanced weight loss. 

It may also help you avoid some of the downsides of following a ketogenic diet. This includes the notorious “keto flu” that occurs shortly after starting a keto diet and causes symptoms such as headache, fatigue, nausea, and brain fog.1 

The keto diet may also raise your LDL-cholesterol (the so-called “bad” cholesterol), cause dehydration and electrolyte imbalances, and lead to constipation due to the lack of fiber in the diet.1    

When to Take Keto OS Supplements?

Many people take ketones before and during exercise or before an athletic event to give them extra energy and focus.  

They can also be used to help improve mental energy and focus to help you with work, studying, or reading. 

It’s best to take Keto OS NAT on an empty stomach, such as first thing in the morning. Not only are the ketones absorbed better, but eating a meal already gives your body the energy it needs which makes ketones unnecessary.  

You should avoid taking them before bed as the extra energy it gives you may interfere with your sleep.  

Prüvit recommends you take at least two servings of Keto OS NAT a day for optimal performance.  

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Benefits of Keto OS NAT

Although research is limited, studies have found multiple benefits of supplementing with exogenous ketones like those found in Keto OS NAT.

1. Controls your appetite and may help with weight loss

By keeping your appetite in check, ketones may help you lose weight.  

In one study, people taking a ketone supplement reported less hunger compared to those consuming a sugary drink.5 

Ketones work by reducing levels of the hormone ghrelin, which stimulates appetite and is normally elevated during weight loss.5 

While ketone supplements have never been tested for weight loss benefits in humans, they have led to increased weight loss in mice.6  

However, there may be certain benefits to the ketogenic diet that you can’t get by supplementing ketones. 

2. May Improve Exercise Performance

Ketones may help you perform better in the gym. During intense exercise, the body requires more glucose to use as fuel. When it can’t get enough glucose, your performance suffers.

By giving your body an alternative energy source, ketones help spare glucose. This means you’ll have more energy to exercise as you don’t have to rely solely on glucose. 

In one study of 39 elite athletes, ketone supplementation improved endurance.7 

3. Improves Blood Sugar Levels

Taking exogenous ketones has been shown to significantly lower blood sugar levels.8 High blood sugar levels can damage the eyes, kidneys, nerves, and blood vessels and are linked to an increased risk of heart disease.9  

4. May help slow cognitive decline and support overall brain health

Ketones may help people who have Alzheimer’s disease or are struggling with cognitive decline. 

Alzheimer’s disease reduces the brain’s ability to use glucose for energy. Ketones help sidestep this issue by providing an alternate source of energy.10

Ketone supplementation improved cognitive function and memory in study of 20 people with either mild cognitive impairment and Alzheimer’s disease.10 

Ketone supplements may also help protect the brain from damage caused by Parkinson’s disease by reducing inflammation.11

5. Allows you to experience the benefits of following a strict ketogenic diet without doing so

This is arguably one of the most appealing benefits of taking ketone supplements. They allow you to enter ketosis without having to greatly reduce your carb intake or suffer through the “keto flu.” 

You can also reach ketosis quicker without having to wait days or weeks.

Is Keto OS NAT safe?

Yes, Keto OS NAT is safe for most people

People who are sensitive to caffeine may want to opt for the caffeine-free version (Uncharged).

Type 2 diabetics who are taking medications to lower their blood sugar levels should speak with their doctor before taking ketone supplements, as they can further lower your blood sugar.8

Potential Keto OS NAT Side Effects

There are potential side effects to ketones supplements including:1,12

  • Bad breath and/or foul taste in the mouth
  • Very low blood sugar levels (hypoglycemia)
  • Upset stomach 
  • Diarrhea and constipation
  • Gas
  • Nausea and vomiting

My Keto OS NAT Ketones Review — Pros and Cons

Things I Like About Keto OS NAT 

1. It gave me a sustained boost of energy and improved focus 

During my month-long trial, I swapped out my coffee for the caffeine-free version (“Uncharged”)  of Keto OS NAT. Normally, I experience a significant dip in my energy levels when I take a break from coffee, but this wasn’t the case when I was taking Keto OS NAT.  

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Will Hunter / KnowYourDNA

Instead, I felt a subtle increase in energy that lasted for hours. It was a clean energy boost, markedly different from the one I would get drinking coffee that can tend to make me feel jittery or tense.   

I also experienced increased focus and mental clarity. It was just easier to keep my attention from wavering and really hone in on the task at hand. 

2. It tastes great

Prüvit really nailed it on the flavor. It’s sweet but not overly-sweet and doesn’t leave any weird aftertaste in your mouth. 

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They also have a wide selection of flavors–12 flavors that are available year-round and 10 seasonal flavors–so you’re sure to find something you like. The variety is nice to have if you have a picky palate or plan on becoming a regular consumer of Keto OS NAT and want to switch things up occasionally.

3. It reduced my hunger

I practice a 16-8 intermittent fasting schedule most days (16 hours fasting with an 8-hour feeding window). I usually rely on caffeine to help control my appetite. However, Keto OS NAT was much more effective in keeping the hunger pangs away than coffee or tea.   

4. It put me into ketosis fast

Keto OS NAT raises your ketone levels quickly. I found that within one hour of taking one packet on an empty stomach, my ketone levels rose to around 5 mg/dL–about the level I would reach following a strict ketogenic diet.

Things I Don't Like About Keto OS NAT 

1. It doesn’t list the amount of caffeine per serving

The packaging for the “Charged” version says it contains as much caffeine as a 12-16 oz cup of coffee. That is a wide range of coffee that makes it unhelpful in determining the caffeine content in Keto OS NAT. Additionally, the amount of caffeine in coffee varies considerably depending on the roast, brewing method, and origin of the beans. 

I’m not quite sure why they chose not to reveal the exact amount of caffeine per serving. It seems like this number would be easy enough to obtain from testing. For people who are caffeine sensitive or want to limit their intake, knowing the exact amount of caffeine in a supplement is important. 

2. It’s high in sodium 

At 910 mg, Keto OS NAT contains nearly 40% of the daily value (%DV) of sodium. This can put you over the edge in terms of your daily sodium intake, especially if you’re already getting enough from food. 

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Will Hunter / KnowYourDNA

This isn’t much of an issue for people who regularly engage in intense exercise as you lose a lot of sodium in your sweat. However, people who are watching their salt intake due to high blood pressure or other health reasons may want to avoid Keto OS NAT.   

3. It’s fairly expensive

At $6.5 per serving, Keto OS NAT is one of the more expensive ketone supplements on the market. While signing up for a subscription lowers this cost to $5/serving, it’s still costly.

You’ll have to determine for yourself if the possible benefits are worth it.

4. It produced a strange, metallic taste in my mouth

Just like a keto diet, ketone supplements can create a weird taste in your mouth. This is due to acetone, a byproduct of ketones that you exhale. Brushing only slightly improved the taste. 

Should You Take Keto OS NAT?

If you want to experience many of the benefits of ketones without having to follow a strict ketogenic diet or experience its downsides, Keto OS NAT is a great option for you. Keto OS NAT may be especially helpful for athletes or those performing tasks that require lots of mental and physical energy and focus.

While there is evidence that ketones may help control appetite, slow cognitive decline, and improve athletic performance, research is still limited.

For some people, the high of Keto OS NAT may outweigh any purported benefits. Thankfully, Prüvit allows you to return the unused portion of the product within 30 days for a full refund if you’re not satisfied. 

Others may want to wait until more research has confirmed the benefits and risks of ketone supplements.

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Updated on February 27, 2023
Will Hunter
Will Hunter
Content Contributor
Will is a content writer for KnowYourDNA. He received his B.A. in Psychology from the University of California, Los Angeles. Will has 7 years of experience writing health-related content, with an emphasis on nutrition, alternative medicine, and longevity.
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