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Best Supplements for Gut Health & Digestion
Updated on December 5, 2022
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Best Supplements for Gut Health & Digestion
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Most digestive supplements contain probiotic bacteria. Taking them encourages good bacteria to thrive and prevents bad bacteria from taking over.

Probiotic supplements treat gut flora imbalance and relieve some digestive issues, such as:

  • Frequent bloating and gas
  • Leaky gut syndrome
  • Antibiotic-associated diarrhea (AAD)

However, you need more than a balanced gut bacteria to have healthy digestion.

Best Supplements for Gut Health & Digestion 7

Better Digestion with Healthy Gut Supplements

Your digestive system plays an essential role. It turns the foods we eat into energy and uses them to repair or grow cells. Some signs of a healthy gut include being able to:

  • Break down food without digestive symptoms
  • Absorb nutrients from the foods you eat
  • Dispose food wastes with relatively no discomfort

When you eat the worst foods for your gut and make unhealthy choices, it will hurt your digestive tract. Certain infections and diseases may also affect its function.

You’ll need supplements to aid digestion, relieve symptoms, and help with other gut-related concerns. We prepared a list of the best gut health supplements you can try.

5 Best Supplements for Digestive Health

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ONNIT Total Gut Health — Best Gut Health Supplement

Cost: About $75.90 per month (30 servings)

ONNIT is dedicated to total human optimization (THO). The company develops products that can transform your body and your life. These include:

  • Dietary supplements
  • Nutrition snacks
  • Home workout equipment
  • Fitness apparel

One of their products is Total Gut Health™ with Probiotics

Best Supplements for Gut Health & Digestion 8

Onnit Total Gut Health

Total Gut Health Gets our recommendation because it's one of the highest quality gut health supplements on the market.

ONNIT Total Gut Health Review

What I Like: Total Gut Health isn’t just a probiotic. It’s a complete digestive health supplement that contains a unique blend. These include:

  • Probiotics to balance your good and bad bacteria
  • Prebiotics to nourish your good gut bacteria
  • Digestive enzymes that help with digestion and nutrient absorption
  • Healthy yeasts relieve digestive problems
  • Betaine HCl supports digestion and kills harmful bacteria

It only uses ingredients backed by science, which means it delivers results as promised. It’s caffeine-free, dairy-free, and soy-free. 

Total Gut Health is also safe for people who follow vegan and keto weight loss diets.

What I Don’t Like: It isn’t tailored to your needs. Total Gut Health is an over-the-counter digestive supplement. Yet it costs more than Ombre, which offers personalized probiotics.

We still recommend it if you have frequent bloating, gas, diarrhea, and indigestion. But if you have specific needs like weight loss and better focus, it isn’t for you.

Read our ONNIT Total Gut Health Reviews.

Colon Broom — Best Fiber Supplement for Weight Loss and Constipation

Cost: About $68.99 per month (30 servings)

Whole plant-based foods like fruits and vegetables contain fibers. Fiber provides many health benefits. It can:

  • Regulate your bowel movement
  • Lower your cholesterol levels
  • Keep your blood sugar under control
  • Reduce your appetite and calorie intake
  • Support your weight loss efforts

Colon Broom is a fiber supplement that offers similar benefits as dietary fiber.

Best Supplements for Gut Health & Digestion 9

Colon Broom

Colon Broom is a whole planet-based supplement; full of fiber and perfect for keeping your colon in check.

Colon Broom Reviews

What I Like: Colon Broom contains Psyllium husk. It’s a soluble fiber that attracts water when it passes through your gut. It slows your digestion and promotes regular bowel movements.

It can be helpful if you suffer from an overactive gut, such as diarrhea and irritable bowel syndrome. It relieves constipation, hemorrhoids, and other gut problems.

Fiber adds bulk to your diet. Fiber supplements can help you lose weight when paired with a fiber-rich diet. They can decrease your appetite and how much food you eat in a day. 

Studies show that Psyllium lowers cholesterol and blood glucose levels. It can reduce your risk for diabetes, heart disease, and colon cancer.

What I Don’t Like: Fiber supplements are safe for daily use, but they might cause digestive symptoms. The Psyllium in Colon Broom increases your risk.

You’re more likely to experience bloating, gas, cramping, and flatulence if you take large doses of soluble fiber. Eating only 30 grams of per day will help you avoid the side effects of fiber.

Read our Colon Broom Reviews.

Now Super Enzymes — Best Digestive Enzymes for Indigestion

Cost: About $21.99 per month (30 servings)

The body produces its own digestive enzymes to break down food. Some people don’t make enough of them — a condition known as digestive enzyme insufficiency.

Conditions like Celiac disease and inflammatory bowel disease (IBD) may also cause your body to stop producing certain digestive enzymes. These can affect the way your body digests food. 

It can lead to indigestion and other digestive symptoms like:

  • Abdominal pain
  • Bloating
  • Gas
  • Heartburn

Now Foods Super Enzymes may help you digest foods and reduce your symptoms. 

Now Super Enzymes Review

What I Like: It contains a comprehensive blend of ingredients that will help your body digest different types of food. These include:

  • Major digestive enzymes
  • Betaine hydrochloride (HCl)
  • Ox bile extract
  • Papaya fruit powder
  • Cellulase

Amylase, protease, and lipase are the three major enzymes produced by the body. They digest the carbohydrates, proteins, and fats in food.

Betaine HCl stimulates the production of hydrochloric acid. It works together with digestive enzymes to aid your body in digestion and nutrient absorption. It also kills bacteria in food.

Ox bile extract is a dietary supplement used to replace bile. Bile is a pancreatic acid essential for breaking down fats into fatty acids. Doctors prescribe animal-derived enzymes (like ox bile) to treat people deficient in pancreatic enzymes.

Papaya fruit powder contains two enzymes, papain and chymopapain. Both help digest proteins and reduce gut inflammation. 

Finally, there’s cellulase — an enzyme that is naturally produced by gut bacteria. It breaks down cellulose, an insoluble fiber found in green leafy vegetables.

What I Don’t Like: Currently, there is little proof that digestive enzyme supplements are good for digestion. Research does show they may have use for digestive enzyme therapy.

Another drawback of Now Foods Super Enzymes is you have to take it with every meal.

Best Supplements for Gut Health & Digestion 10

Now Super Enzymes

Lovebug Yeast Is A Beast — Best Probiotics for Women

Cost: About $24.95 per month (30 servings)

Women are prone to bacterial vaginosis, yeast infections, and urinary tract infections. It happens when harmful bacteria and yeasts outnumber healthy microorganisms.

Lovebug Yeast Is A Beast is the best probiotic supplement for women. It can restore your gut flora balance while protecting you against these common infections.

Lovebug Probiotics Review

What I Like: Lovebug Yeast Is A Beast has 5 strains of beneficial gut bacteria:

  • Lactobacillus plantarum
  • Lactobacillus rhamnosus
  • Bifidobacterium lactis
  • Lactobacillus paracasei
  • Lactobacillus casei

Each capsule also contains 500 mg of cranberry fruit powder, so it isn’t just a probiotic. Cranberry supplements have been shown to reduce the incidence of UTIs in healthy women.

Lactobacilli decrease gut inflammation and reduce symptoms of irritable bowel syndrome (IBS). People who exhibit signs of common food intolerances may benefit from supplements.

Studies show it can bolster your immunity, prevent gut infections, and treat diarrhea caused by antibiotics. L. plantarum and rhamnosus may even protect you against vaginal infections.

Bifidobacteria enhances the bioavailability and effectivity of lactobacilli strains.

What I Don’t Like: According to Dr. Caroline Mitchell, an assistant professor at the Harvard Medical School, there is almost no evidence that probiotics are good for vaginal health.

Dr. Mitchell does acknowledge that women with recurring vaginal infections can benefit from them — at least, in theory.

Best Supplements for Gut Health & Digestion 11

Lovebug Probiotics

Garden of Life Mood+ Probiotics — Best Probiotics for Men

Cost: About $47.99 per month (30 servings)

Men are more likely than women to not do anything about their stress. Chronic stress can have a negative impact on your mood, daily function, and mental health.

Garden of Life Mood+ may be beneficial for men who are under a lot of stress. It’s said to promote relaxation, enhance mood, and support emotional wellbeing.

Garden of Life Mood+ Probiotics Reviews

What I Like: Garden of Life produces doctor-formulated dietary supplements. Each one is designed to help with specific health concerns. Mood+ Probiotics is no exception to this rule.

Despite its name, it’s more than a probiotic. Each capsule contains:

  • Probiotics
  • Prebiotic (potato)
  • Ashwagandha extract
  • Blueberry extract

It has a total of 16 probiotic strains, including lactobacilli and bifidobacteria. The combination enhances gut flora diversity and protects you against pathogens, including rotavirus.

Garden of Life Mood+ also has L. helveticus and B. longum in its blend. Early studies show they can be beneficial for anxiety and depression.

Prebiotics like potatoes are foods that promote gut health. They nourish your good gut bacteria to thrive so harmful bacteria can’t take over.

Ashwagandha extract is an adaptogen that helps your body respond to stressful situations. It’s proven to stabilize the mood of people who are anxious and depressed. 

Evidence suggests that daily blueberry supplements may lessen symptoms of depression.

What I Don’t Like: The science linking mood with probiotic supplements is still in its early stages. But they have shown the potential to improve mood, cognition, stress, and anxiety.

We recommend taking the Vessel Health test to monitor your stress levels. It has an accompanying app that will teach you ways to lower your stress.

Best Supplements for Gut Health & Digestion 12

Garden of Life Mood+

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Resources

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  1. Probiotics: What You Need To Know.” National Center for Complementary and Integrative Health.
  2. Dietary Fiber.” MedlinePlus.
  3. Soluble vs. Insoluble Fiber.” MedlinePlus.
  4. Psyllium.” Mount Sinai Health System.
  5. Digestive Enzymes and Digestive Enzyme Supplements.” Hopkins Medicine.
  6. Bile Acid Replacement in Bile Acid Synthesis Defects.” Lippincott.
  7. Digestive Enzyme Supplementation in Gastrointestinal Diseases.” National Center for Biotechnology Information. 
  8. Mechanisms and therapeutic effectiveness of lactobacilli.” National Center for Biotechnology Information. 
  9. Cranberry Reduces the Risk of Urinary Tract Infection Recurrence in Otherwise Healthy Women: A Systematic Review and Meta-Analysis.” Oxford Academic. 
  10. Should you use probiotics for your vagina?” Harvard Health Publishing.
  11. Comparison of probiotic lactobacilli and bifidobacteria effects, immune responses and rotavirus vaccines and infection in different host species.” National Center for Biotechnology Information. 
  12. The Efficacy, Safety, and Tolerability of Probiotics on Depression: Clinical Results From an Open-Label Pilot Study.” Frontiers In Psychiatry.
  13. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers.” Taylor & Francis Online. 
  14. An Overview on Ashwagandha: A Rasayana (Rejuvenator) of Ayurveda.” National Center for Biotechnology Information.
  15. Effect of 4 weeks daily wild blueberry supplementation on symptoms of depression in adolescents.” National Center for Biotechnology Information.Probiotics may help boost mood and cognitive function.” Harvard Health Publishing.
Ada Sandoval
Ada Sandoval
Content Contributor
Ada Sandoval is a B.S. in Nursing graduate and a registered nurse with a heart for abandoned animals. She works as a content writer who specializes in medical-related articles and pet health.
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