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Best Probiotics for Men (2024)
Updated on January 31, 2024
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Best Probiotics for Men (2024)

You’ve probably heard how important probiotics are for your digestive system. Probiotic supplements help break down your food, keep bad bacteria at bay, and ensure your digestion runs smoothly. 

But the benefits of probiotics extend beyond a healthy gut. They can be good for your heart, skin, mental performance, and immune function.

Nearly everyone can benefit from probiotic supplements. But are there any benefits that are unique to men? Let’s take a closer look. 

Best Probiotic Supplements for Men

How We Chose the Best Probiotic for Men

We focused on each probiotic’s health benefits and took price, convenience, and accessibility into consideration, as well.

After determining which probiotics performed the best, we determined which probiotic would be best for specific benefits.

Some men want to feel healthier overall, others want specific boosts in terms of digestive health or their immune system. We evaluated each probiotic’s success in terms of its goals and if the research and science behind them were sound.

Best Probiotic Strains for Men

These are just some strains you might want to look out for in a probiotic supplement:

  • Lactobacillus acidophilus – Good for balancing the gut
  • Lactobacillus fermentum – Good for the immune system
  • Lactobacillus rhamnosus – Good for relieving digestive issues
  • Bifidobacterium longum ssp. Longum — Good for preventing inflammation and digestive issues
  • Bifidobacterium animalis ssp. Lactis — Good for preventing infection

For biological men, these are the specific probiotic strains that may benefit you most and boost testosterone and/or prostate health:

  • Lactobacillus reuteri 
  • Lactobacillus acidophilus
  • Lactobacillus casei
  • Pseudomonas
  • Gardnerella

Remember that different probiotic strains provide different additional benefits. Probiotics, in general, will help you out in a holistic manner—it’s up to you to figure out if you also want an extra boost for your immune system, testosterone, digestive health, etc.

The probiotic strain you want to focus on may work well with others, so take that into consideration as well.

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Our review of the best at-home Microbiome Tests.

Best Probiotic Supplements for Men

Here are the top probiotics we recommend for men’s health:

PriceFormNotable strains/ingredientsCFUs
Viome Precision$139.00CapsuleDepends on resultsN/A
Ombre Endless Energy$39.99CapsuleSaccharomyces boulardii
Lactobacillus paracasei
5 billion
Ombre Mood Enhancer$39.99CapsuleBifidobacterium longum
Lactobacillus plantarum
Lactobacillus rhamnosus
10 billion
Garden of Life$32.84CapsuleAcidophilus50 billion
Nature Target$16.99CapsuleBifidobacterium
60 billion

Best Personalized Probiotics — Viome Precision

Price: Starts at $139.00 per month (includes the Gut Intelligence Test)

About Viome Precision

Viome offers gut health tests that analyze your microbiome. The company uses your test results to suggest probiotics, prebiotics, and supplements suited to your needs. Once it has an idea of what you need, it will offer a customized probiotic supplement.

Currently, Viome offers three supplement bundles:


With Viome, you don’t just get a preformulated blend. They offer personalized supplements that are tailored to each person’s needs.

These supplements contain herbs, vitamins, minerals, and amino acids that can help support a man’s health. They also have food extracts and digestive enzymes to aid in digestion and help curb problems like irritable bowel syndrome.

You’ll also get probiotic and prebiotic suggestions and other actionable steps that can balance your gut flora and improve your overall health, not just gut health.


Before you can get Viome’s personalized recommendations, you have to take their test. It’s a price you have to be willing to pay.

There’s also a bit of waiting time involved. It can take 3 to 4 weeks for your test results to arrive.

Use code for 15% off on the first three months if you subscribe

Best Probiotic for Energy — Ombre Endless Energy

Price: Starts at $39.99 with a one-time purchase (you can subscribe and save up to 25% off) 

About Ombre Endless Energy

Ombre Endless Energy is a prebiotic and probiotic formula. It supports energy and focus and enhances physical and mental performance.

It contains a unique blend of probiotic strains that strengthen the gut barrier and gut health.

This improves nutrient absorption and prevents toxins and undigested food from passing through the gut, which can cause inflammation, brain fog, and fatigue.

Endless Energy may also increase the production of short-chain fatty acids (SFAs). This helps reduce inflammation and regulate blood sugar, so you don’t experience crashes.


It includes prebiotic fibers that help feed beneficial bacteria and support gut health.

The strains in Ombre Endless Energy can also withstand stomach acid and bile. It allows them to make their way to the colon, where they provide the most benefit. 

You can take it with or without a meal, which is very convenient. It’s unique in that it contains these bacteria in its probiotic supplement:

  • Saccharomyces boulardii — This probiotic yeast helps repair the gut lining and improves digestion, gut health, and nutrient absorption. 
  • Lactobacillus paracasei — Has been shown to reduce stress and improve sleep. 

Ombre Endless Energy is caffeine-free, so you don’t have to worry about jitters or crashes.


Currently, there is little evidence that the strains used in Endless Energy can reduce brain fog, improve mental and physical performance, and increase energy levels. 

However, its ability to reduce stress, improve sleep, and promote healthy digestion may lead to these outcomes.

Sale: $20 off

Best Probiotic for Mood — Ombre Mood Enhancer

Price: Starts at $39.99 with a one-time purchase (you can subscribe and save up to 25% off) 

About Ombre Mood Enhancer

Ombre Mood Enhancer contains “psychobiotics” or probiotics that benefit your mental health. They’re designed to increase your levels of serotonin. 

Serotonin is the so-called “happy chemical” in the brain. It helps lift your mood and emotion. The hormone also influences your gut health, digestion, and sleep. 

Low levels of serotonin have been linked to depression.15 By boosting serotonin, Ombre’s Mood Enhancer may improve sleep, cognitive function, and stress response.  


The strains used in Ombre Mood Enhancer may increase serotonin production, reduce stress and anxiety, and improve memory and mental performance.

Ombre Mood Enhancer includes:

  • Bifidobacterium longum — protects the gut lining and improves memory and gut health
  • Lactobacillus plantarum — promotes serotonin production and immune health
  • Lactobacillus rhamnosus — supports brain function

Mood Enhancer contains 10 billion CFUs (colony-forming units) per capsule. This refers to the number of live and viable bacteria contained in the probiotic supplement. 

The higher the CFU, the more effective a probiotic supplement is. The probiotics in Mood Enhancer are shelf-stable, so no refrigeration is required.


It doesn’t contain prebiotics, which can help the probiotics better survive the passage through the gut. There is also no solid scientific evidence that the strains used in the supplement improve sleep quality.

Sale: $20 off

Best Probiotics for Prostate Health — Garden of Life

Price: $32.84 on Amazon

About Garden of Life

By taking just two capsules a day, you introduce 50 billion colony-forming units to better aid your digestive system and prostate health. Using clean, traceable ingredients, Garden of Life aims to empower you and your health decisions.


Not only does it serve its purpose as a prebiotic, but it also helps maintain and improve urinary tract and prostate health.

All the cranberries used in the prebiotic are also organically grown and free from any additives or artificial sweeteners.


Considered to be a little pricey, especially since they're more readily available on Amazon and it doesn't have a monthly subscription option.

It also looks like a ton of capsules in the canister, but it goes fast because you're taking two a day.

Best Probiotics for Immune System Health — Nature Target

Price: $16.99 on Amazon

About Nature Target

Serving the dual purpose of probiotic and immune system booster, Nature Target is a great option for anyone looking for their go-to supplement.


Nature Target also contains prebiotics, which is a great plus---especially for its price. 

That will only further enhance gut flora as the probiotics are already given "food" to survive and thrive. Your gut health will only benefit from the healthy bacteria.

The capsule itself is protected by several layers to make it to the digestive tract. Delayed release promises the most efficacy when delivering the healthy bacteria to boost your immune system.

There are also plenty of tablets (90) per order, making it more cost-effective in the long run.


Some people experienced some initial bloating and constipation, which can be uncomfortable for the first few days.

Why You Need to Take Care of Your Gut

Having a healthy gut is vital to your overall health. Unfortunately, an unhealthy lifestyle wreaks havoc on the gut. It exposes us to chronic stress, poor diet, lack of exercise, and antibiotics.

Diets that don’t include diverse, nutrient-dense foods, along with sedentary lifestyles, are often not doing the gut any favors. So you need to stay on top of your gut health to optimize your overall wellness.

Taking care of your gut leads to better overall health. Because the gut is connected to all organ systems, a healthy gut means a healthy body.

Why Should Men Take Probiotics?

Probiotics directly impact and improve gut health. They’re a great way to support your gut and health and encourage beneficial bacteria to grow. Research has shown probiotic supplements to be helpful for:1,2,3

  • Promoting healthy digestion and improving digestive health
  • Supporting regular bowel movements
  • Strengthening the immune system
  • Reducing inflammation
  • Improving blood sugar levels and insulin sensitivity
  • Boosting mood

Men, in particular, may want to start probiotic supplements because many probiotic strains are beneficial for testosterone development. Boosting testosterone and hormone health in men may improve their mood, fertility, and mental health.

Probiotics promote the growth of beneficial bacteria in your gut. These good bacteria contribute to improved immune function, digestion, and overall health.

Probiotic supplements also help balance the gut against “bad” or harmful bacteria. The microbiome is a diverse landscape of bacteria and fungi. Some of these bacteria are beneficial and can contribute to overall wellness. Other bacteria are not quite as good.

Remember that the presence of these “bad” bacteria isn’t a problem in itself. You should be worried when there are too many strains of them. When your gut bacteria is imbalanced (gut dysbiosis), bad bacteria can mess up your gut and, subsequently, your entire body.

Probiotic supplements help combat this imbalance and promote the growth of good bacteria to crowd out the bad.

Signs You May Need Probiotics

Probiotics are generally beneficial and do not require a prescription, but we highly recommend you consult your doctor or healthcare provider before taking them.

When you notice you’re feeling or experiencing the following, it may be time to consider asking your doctor if you should start taking probiotic supplements: 

  • Constant fatigue
  • Digestive health issues (like abdominal pain or irritable bowel syndrome)
  • Brain fog
  • Mood issues
  • Trouble sleeping
  • Sexual dysfunction
  • Autoimmune issues
  • Allergy-like symptoms
  • Skin rashes
  • Extreme cravings
  • Bumps, acne, and skin changes

If you notice any other differences in your day-to-day, you should also tell your doctor about them—they may prescribe probiotics to address them too.

Certain probiotic strains are available for those who may need them. Some probiotic strains will help you boost immunity or digestive health while others are better suited for testosterone and hormone boosts.

Remember to get your doctor’s opinion before taking probiotics; they can give you suggestions and guidance on which ones may benefit you most.

If you also recently took an antibiotic, you may want to look into probiotics. Probiotic strains will help repopulate your gut microbiome and keep any digestive issues that sometimes accompany antibiotics at bay.

Health Benefits of Probiotics for Male Health

Beyond general health benefits, probiotics are great for specific aspects of male health. 

Supports healthy testosterone levels

Testosterone is vital to a man’s health. It impacts their mood, energy, strength, and sexual function. After peaking in their 20’s, their testosterone begins to drop by around 1.5% a year.4 

Gut health appears to play a major role in men’s testosterone levels. Men with a higher diversity of gut microbes (a sign of a healthy gut) have higher testosterone levels.

Low testosterone levels are linked to lower levels of good bacteria and higher levels of bad bacteria in the gut.6 Supplementation with a specific probiotic strain, Lactobacillus reuteri, has been shown to increase testosterone.7

By improving gut health, probiotics may help support healthy testosterone levels.

Keeps the prostate healthy

As men age, they are at a greater risk of benign prostate hyperplasia (BPH). It is a condition that causes the prostate to grow too large.

An enlarged prostate can make it difficult to urinate. You may have a weak stream, urinate more frequently, or fail to empty your bladder.

BPH is very common, occurring in about half of men over the age of 50 and 80% of men over 80.8  Inflammation and diseases like prostate cancer seem to be major causes of BPH.

By creating inflammation, poor gut health may drive uncontrollable growth of the prostate.10

It may help explain why men diagnosed with prostate cancer have higher levels of gut bacteria that promote inflammation.11

Probiotics can potentially keep your prostate healthy by reducing inflammation and improving gut health.

Improving sexual health and fertility

By improving testosterone levels and blood vessel health, probiotics may help men in bed. 

According to one study, men with erectile dysfunction tend to have lower bacterial diversity – one of many signs of poor gut health.12

Inflammation caused by harmful gut bacteria can damage the blood vessels. This reduces blood flow and makes it harder for men to get and sustain erections.

By reducing inflammation, probiotics can improve blood vessel health and erectile function.13 

Probiotics also improve erectile function by increasing nitric oxide levels, a compound that dilates blood vessels and increases blood flow.14 

Inflammation caused by an unhealthy gut microbiome may also damage sperm. 

Infertile men who receive probiotic supplements have higher levels of healthy sperm and lower levels of inflammation and oxidative stress.13

Improved Skin Health

The bacteria in a probiotic supplement can help reduce inflammation in the skin, minimize acne, and even contribute to your skin’s moisture and pH balance.

This is because certain bacteria can boost lipids and ceramides in the skin, which will help you retain moisture.

Moist skin is healthier all around, reducing your chances of developing acne, eczema, and wrinkles.

Because probiotics reduce inflammation in general, your skin is also less likely to become inflamed.

And because probiotics help curb allergic reactions, skin allergies will also happen less frequently.

Support Immune System Health

When it comes to immune health, bacteria in a probiotic supplement can stimulate antibody production and strengthen intestinal immune cells.

A strong gut, by virtue of healthy gut flora, bolsters the cells living in the intestine. Because a diverse congregation of bacteria is beneficial, 70-80% of your immune cells live there.

With a majority of your pathogen-fighting cells enriched by the bacteria from a high quality probiotic supplement, your body will be all the healthier and even more immune.

Strengthening immune health is important to keep infections at bay. 

Improved Digestive Health

If you constantly suffer from digestive problems like irritable bowel syndrome, probiotics may just solve them for you.

Gut imbalances (called dysbiosis) happen when bad bacteria outnumber or overpower beneficial bacteria. This can happen because of a variety of reasons, such as:

  • Poor diet
  • Taking antibiotics
  • Bad hygiene
  • Infection

So if you’re suffering from digestive issues like painful stomach acid or abdominal pain, probiotics may help.

Just like how they optimize immune health, probiotic supplements boost colon health. 

Note: Probiotics may sometimes be prescribed by your doctor along with antibiotics to counter the negative effects of eliminating the bacteria (even beneficial bacteria) in your microbiome. Ask your healthcare provider for more information if you ever need to complete a dose of antibiotics.

Natural Probiotic Foods

If you want to start introducing more probiotic strains to your body without necessarily looking into probiotic supplements, you can always incorporate more of these foods into your diet: 

  • Kimchi
  • Yogurt
  • Kefir
  • Kombucha
  • Pickles
  • Miso
  • Tempeh
  • Sourdough bread
  • Soft cheeses
  • Natto
  • Kvass
  • Pickled beets
  • Apple cider vinegar

Fermented foods in general are great for the gut and are good for diversifying your diet and microbiome.

What Happens When Men Have Poor Gut Health?

Poor gut health can lead to poor health overall.

Because the gut is connected to other organ systems, your body may not feel its best if your gut doesn’t have enough diversity in terms of bacteria and/or the balance is off.

As a man, your testosterone levels may drop and your prostate may suffer. You may also fail to perform sexually as a result.

It’s important to stay on top of gut health in order to keep yourself holistically healthy. 

Symptoms of Poor Gut Health

Here are just a few symptoms of poor gut health:

  • Constant abdominal pain
  • Allergic reactions have become more severe/painful
  • Food intolerances have developed/become more severe
  • Extreme cravings
  • Painful bowel movements
  • Feeling tired, depressed, or constant brain fog
  • Skin problems
  • Inconsistent energy levels
  • Gas and bloating
  • Heartburn

These symptoms will become worse if you don’t make changes in your lifestyle or diet. One easy way to tackle these problems is through probiotics.

Again, always consult your healthcare provider before starting any kind of supplement or diet change.

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Updated on January 31, 2024
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16 sources cited
Updated on January 31, 2024
  1. A review of probiotic supplementation in healthy adults: helpful or hype?” European Journal of Clinical Nutrition
  2. Probiotic Supplements Improve Blood Glucose and Insulin Resistance/Sensitivity among Healthy and GDM Pregnant Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials” Evidence-based Complimentary and Alternative Medicine
  3. Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo-controlled study” Psychology Medicine
  4. Testosterone for the aging male; current evidence and recommended practice” Clinical Interventions in Aging
  5. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome” Research in Microbiology
  6. Correlation Between Gut Microbiota and Testosterone in Male Patients With Type 2 Diabetes Mellitus” Frontiers in Endocrinology 
  7. Probiotic microbes sustain youthful serum testosterone levels and testicular size in aging mice” PLoS One
  8. Epidemiology of clinical benign prostatic hyperplasia” Asian Journal of Urology
  9. Inflammatory mediators in the development and progression of benign prostatic hyperplasia” Nature Reviews. Urology
  10. The microbiome in prostate inflammation and prostate cancer” Prostate Cancer and Prostatic Diseases
  11. The human gastrointestinal microbiota and prostate cancer development and treatment” Investigative and Clinical Urology
  12. Correlation between gut microbiota diversity and psychogenic erectile dysfunction” Translational Andrology and Urology
  13. Probiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men” Human Fertility
  14. Probiotics as Beneficial Dietary Supplements to Prevent and Treat Cardiovascular Diseases: Uncovering Their Impact on Oxidative Stress Oxidative Medicine and Cellular Longevity
  15. Depressive Symptoms are Associated with low Serotonin Levels in Plasma but are not 5-HTTLPR Genotype Dependent in Older Adults” The Spanish Journal of Psychology
  16. The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies” Nutrients
Will Hunter
Will Hunter
Content Contributor
Will is a content writer for KnowYourDNA. He received his B.A. in Psychology from the University of California, Los Angeles. Will has 7 years of experience writing health-related content, with an emphasis on nutrition, alternative medicine, and longevity.
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