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Best Probiotics for Men
Updated on November 28, 2022
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Best Probiotics for Men

You’ve probably heard how important probiotics are for your digestive system. They help break down your food, keep bad bacteria at bay, and ensure your digestion runs smoothly. 

But the benefits of probiotics extend beyond a healthy gut. They can be good for your heart, skin, mental performance, and immune function.

Nearly everyone can benefit from probiotic supplements. But are there any benefits that are unique to men? Let’s take a closer look. 

Why Men Need to Take Care of Their Gut

Having a healthy gut is vital to your overall health. Unfortunately, a modern lifestyle wreaks havoc on the gut. It exposes us to chronic stress, poor diet, lack of exercise, and antibiotics.

Probiotics are a great way to support your gut and health. Research has shown probiotic supplements to be helpful for:1,2,3

  • Promoting healthy digestion
  • Supporting regular bowel movements
  • Strengthening the immune system
  • Reducing inflammation
  • Improving blood sugar levels and insulin sensitivity
  • Boosting mood

Best Probiotic Supplements for Men

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Health Benefits of Probiotics for Male Health

Beyond general health benefits, probiotics are great for specific aspects of male health. 

Supports healthy testosterone levels

Testosterone is vital to a man’s health. It impacts their mood, energy, strength, and sexual function. After peaking in their 20’s, their testosterone begins to drop by around 1.5% a year.4 

Gut health appears to play a major role in men’s testosterone levels. Men with a higher diversity of gut microbes (a sign of a healthy gut) have higher testosterone levels.

Low testosterone levels are linked to lower levels of good bacteria and higher levels of bad bacteria in the gut.6 Supplementation with L. reuteri has been shown to increase testosterone.7

By improving gut health, probiotics may help support healthy testosterone levels.  

Keeps the prostate healthy

As men age, they are at a greater risk of benign prostate hyperplasia (BPH). It is a condition that causes their prostate to grow too large.

An enlarged prostate can make it difficult to urinate. You may have a weak stream, urinate more frequently, or fail to empty your bladder.

BPH is very common, occurring in about half of men over the age of 50 and 80% of men over 80.8  Inflammation and diseases like prostate cancer seem to be major causes of BPH.

By creating inflammation, poor gut health may drive uncontrollable growth of the prostate.10

It may help explain why men diagnosed with prostate cancer have higher levels of gut bacteria that promote inflammation.11

Probiotics can potentially keep your prostate healthy by reducing inflammation and improving gut health.

Improving sexual health and fertility

By improving testosterone levels and blood vessel health, probiotics may help men in bed. 

According to one study, men with erectile dysfunction tend to have lower bacterial diversity – one of many signs of poor gut health.12

Inflammation caused by harmful gut bacteria can damage the blood vessels. This reduces blood flow and makes it harder for men to get and sustain erections. 

By reducing inflammation, probiotics can improve blood vessel health and erectile function.13 

Probiotics also improve erectile function by increasing nitric oxide levels, a compound that dilates blood vessels and increases blood flow.14 

Inflammation caused by an unhealthy gut microbiome may also damage sperm. 

Infertile men who receive probiotic supplements have higher levels of healthy sperm and lower levels of inflammation and oxidative stress.13

Best Probiotic Supplements for Men

Here are the top probiotics we recommend for men’s health:

Best Personalized Probiotics — Viome Precision

Price: Starts at $59.90 per month (includes the Gut Intelligence Test)

Viome offers gut health tests that analyze your microbiome. The company uses your test results to suggest probiotics, prebiotics, and supplements suited to your needs.

Currently, Viome offers three supplement bundles:

Viome Review for Precision Supplements

What I Like: With Viome, you don’t just get a preformulated blend. They offer personalized supplements that are tailored to each person’s needs.

These supplements contain herbs, vitamins, minerals, and amino acids that can help support a man’s health. They also have food extracts and digestive enzymes to aid in digestion.

You’ll also get probiotic and prebiotic suggestions and other actionable steps that can balance your gut flora and improve your overall health.

What I Don’t Like: Before you can get Viome’s personalized recommendations, you have to take their test. It’s a price you have to be willing to pay.

There’s also a bit of waiting time involved. It can take 3 to 4 weeks for your test results to arrive.

Use code for 15% off on the first three months if you subscribe

Best Probiotic for Energy — Ombre Endless Energy

Price: Starts at $39.99 with a one-time purchase (you can subscribe and save up to 25% off) 

Ombre Endless Energy is a prebiotic and probiotic formula. It supports energy and focus and enhances physical and mental performance.

It contains a unique blend of probiotic strains that strengthen the gut barrier. 

This improves nutrient absorption and prevents toxins and undigested food from passing through the gut, which can cause inflammation, brain fog, and fatigue.

Endless Energy may also increase the production of short-chain fatty acids (SFAs). This helps reduce inflammation and regulate blood sugar, so you don’t experience crashes.

Ombre Probiotics Review for Endless Energy

What I Like: It includes prebiotic fibers that help feed beneficial bacteria and support gut health.

The strains in Ombre Endless Energy can also withstand stomach acid and bile. It allows them to make their way to the colon, where they provide the most benefit. 

You can take it with or without a meal, which is very convenient. It’s unique in that it contains these probiotics:

  • Saccharomyces boulardii — This probiotic yeast helps repair the gut lining and improves digestion and nutrient absorption. 
  • Lactobacillus paracasei — Has been shown to reduce stress and improve sleep. 

Ombre Endless Energy is caffeine-free, so you don’t have to worry about jitters or crashes.

What I Don’t Like: Currently, there is little evidence that the strains used in Endless Energy can reduce brain fog, improve mental and physical performance, and increase energy levels. 

However, its ability to reduce stress, improve sleep, and promote healthy digestion may lead to these outcomes.

Extended Cyber Monday: $20 off

Best Probiotic for Mood — Ombre Mood Enhancer

Price: Starts at $39.99 with a one-time purchase (you can subscribe and save up to 25% off) 

Ombre Mood Enhancer contains “psychobiotics” or probiotics that benefit your mental health. They’re designed to increase your levels of serotonin. 

Serotonin is the so-called “happy chemical” in the brain. It helps lift your mood and emotion. The hormone also influences your digestion and sleep. 

Low levels of serotonin have been linked to depression.15 By boosting serotonin, Ombre’s Mood Enhancer may improve sleep, cognitive function, and stress response.  

Ombre Probiotics Review for Mood Enhancer

What I Like: The strains used in Ombre Mood Enhancer may increase serotonin production, reduce stress and anxiety, and improve memory and mental performance.

Ombre Mood Enhancer includes:

  • Bifidobacterium longum — protects the gut lining and improves memory 
  • Lactobacillus plantarum — promotes serotonin production and immune health
  • Lactobacillus rhamnosus — supports brain function

Mood Enhancer contains 10 billion CFUs (colony-forming units) per capsule. This refers to the number of live and viable bacteria contained in the probiotic supplement. 

The higher the CFU, the more effective a probiotic supplement is. The probiotics in Mood Enhancer are shelf-stable, so no refrigeration is required.  

What I Don’t Like: It doesn’t contain prebiotics, which can help the probiotics better survive the passage through the gut. There is also no evidence that the strains used in the supplement improve sleep quality.  

Extended Cyber Monday: $20 off

Best Probiotic for Digestion — Designs For Health ProbioMed 50

Price: Starts at $55.25 with a one-time purchase

Healthy digestion relies on a diverse population of gut bacteria that assist in breaking down food and absorbing nutrients. ProbioMed 50 has multiple probiotic strains that promote:

  • Healthy digestion and elimination
  • Mucosal lining health
  • Bacterial diversity
  • Overall bowel function

It can help with gas and bloating, constipation, and stomach pains.

Designs For Health Review for ProbioMed 50

What I Like: It includes a diverse blend of 10 shelf-stable probiotics. All of the strains in ProbioMed 50 have been well-studied for promoting healthy digestion.

One of these strains is Lactobacillus acidophilus DDS®-1. Several studies show it may be effective for constipation, irritable bowel syndrome, and other digestive disorders.

Another is Lactobacillus rhamnosus, which helps prevent harmful bacteria from colonizing the gut and causing digestion problems.

ProbioMed 50 uses delayed-release technology to ensure the probiotics make it to the colon alive. It contains 50 billion CFUs per capsule, making it a very potent probiotic supplement. 

The label also lists precisely how many CFU are included for each strain.

What I Don’t Like: It’s expensive for a probiotic supplement. Some people may experience digestive upset from its diverse number of strains and high concentration of probiotics.

Best Probiotic for Immunity — Pure Encapsulations Probiotic IMM

Price: Starts at $37.15 with a one-time purchase

The gut plays a crucial role in the immune system. Around 70-80% of immune cells are found in the gut. Gut microbes can affect your immune health either positively or negatively.16  

Probiotic IMM is designed to support a healthy immune system and reduce inflammation. It can help protect your eyes, nose, and throat from harmful viruses and bacteria. 

Pure Encapsulations Review for Probiotic IMM

What I Like: Pure Encapsulations Probiotic IMM helps balance the immune system and control your allergies. It contains Bifidobacterium lactis and Bifidobacterium lactis, which can boost your immunity and help fight upper respiratory illnesses. 

It can be taken with or without a meal and is shelf-stable. It’s manufactured according to strict quality control standards and is free of unnecessary binders, fillers, and preservatives. 

What I Don’t Like: The number of CFUs (5 billion) may be too low to have a large enough effect on the immune system.

Best Probiotic for Skin — Douglas Laboratories Skin Probiotic+

Price: Starts at $34.15 with a one-time purchase

Skin health is intimately linked to the health of your gut. Researchers call it the gut-skin axis. 

Skin Probiotic+ combines clinically-studied probiotics with antioxidant carotenoids to protect the skin from environmental damage and improve skin hydration and elasticity. 

Douglas Laboratories Review for Skin Probiotic+ 

What I Like: Skin Probiotic+ includes powerful ingredients that support skin health and appearance. These include:  

  • Lactobacillus paracasei 
  • Lactobacillus johnsonii
  • Vitamin A
  • Astaxanthin
  • Lycopene 

The probiotics help reduce inflammation in the skin and protect it from damage. 

Carotenoids (astaxanthin and lycopene) produce a synergistic effect and help protect the skin from oxidative stress and UV radiation. 
What I Don’t Like: It only contains two probiotic strains when other effective strains are shown to improve skin health.

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  1. A review of probiotic supplementation in healthy adults: helpful or hype?” European Journal of Clinical Nutrition
  2. Probiotic Supplements Improve Blood Glucose and Insulin Resistance/Sensitivity among Healthy and GDM Pregnant Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials” Evidence-based Complimentary and Alternative Medicine
  3. Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo-controlled study” Psychology Medicine
  4. Testosterone for the aging male; current evidence and recommended practice” Clinical Interventions in Aging
  5. Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome” Research in Microbiology
  6. Correlation Between Gut Microbiota and Testosterone in Male Patients With Type 2 Diabetes Mellitus” Frontiers in Endocrinology 
  7. Probiotic microbes sustain youthful serum testosterone levels and testicular size in aging mice” PLoS One
  8. Epidemiology of clinical benign prostatic hyperplasia” Asian Journal of Urology
  9. Inflammatory mediators in the development and progression of benign prostatic hyperplasia” Nature Reviews. Urology
  10. The microbiome in prostate inflammation and prostate cancer” Prostate Cancer and Prostatic Diseases
  11. The human gastrointestinal microbiota and prostate cancer development and treatment” Investigative and Clinical Urology
  12. Correlation between gut microbiota diversity and psychogenic erectile dysfunction” Translational Andrology and Urology
  13. Probiotic effects on sperm parameters, oxidative stress index, inflammatory factors and sex hormones in infertile men” Human Fertility
  14. Probiotics as Beneficial Dietary Supplements to Prevent and Treat Cardiovascular Diseases: Uncovering Their Impact on Oxidative Stress Oxidative Medicine and Cellular Longevity
  15. Depressive Symptoms are Associated with low Serotonin Levels in Plasma but are not 5-HTTLPR Genotype Dependent in Older Adults” The Spanish Journal of Psychology
  16. The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies” Nutrients
Will Hunter
Will Hunter
Content Contributor
Will is a content writer for KnowYourDNA. He received his B.A. in Psychology from the University of California, Los Angeles. Will has 7 years of experience writing health-related content, with an emphasis on nutrition, alternative medicine, and longevity.
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